Largest Employers
| Company | County | Total Employees | Description |
| Covenant Health | Regional | 10,419 | Health care system |
| Knox County Schools | Knox | 7,881 | Public education system |
| US Dept of Energy; Y-12 National Security Complex | Anderson | 7,000 | Refurbishing nuclear weapon components and storage and recycling of nuclear material. |
| The University of Tennessee - Knoxville | Knox | 6,689 | State university |
| Wal-Mart Stores, Inc. | Regional | 5,951 | Discount stores and wholesale clubs |
| University of Tennessee Medical Center | Knox | 5,316 | Health care system |
| DENSO Manufacturing Tennessee, Inc. | Blount | 4,439 | Advanced automotive components and systems |
| Tennova Healthcare | Regional | 4,001 | Local health care system |
| Dollywood Co./Dollywood Splash Country | Sevier | 4,000 | Theme park and water park |
| State of Tennessee - Regional Offices | Knox | 3,529 | State administrative offices |
| K-VA-T Food Stores (Food City) | Regional | 3,328 | Grocery stores and pharmacies |
| Knox County Government | Knox | 3,204 | County government |
| Tennessee Valley Authority (TVA) | Knox | 3,017 | Regional power authority & development agency |
| Kroger Co. | Regional | 2,952 | Grocery stores |
| McDonald/s Corp; Brothers Management | Knox | 2,846 | McDonald's franchise |
| Sevier County Schools | Sevier | 2,750 | Public education system |
| City of Knoxville | Knox | 2,637 | Municipal government |
| Tanger Five Oaks | Sevier | 2,500 | Retail |
| Clayton Homes, Inc. | Regional | 2,457 | Manufactured and modular homes; financier & insurer of manufactured homes |
| Blount Memorial Hospital | Blount | 2,387 | Area hospital |
| Team Health, Inc. | Knox/Blount | 2,260 | Health care providers |
| Pilot Flying J | Regional | 1,893 | Retail convenience stores and travel centers |
| East Tennessee Children's Hospital | Knox | 1,859 | Area children's hospital |
| Yum! Brands RSC | Regional | 1,853 | Fast food restaurants |
| Roark Capital Group | Regional | 1,830 | Fast food restaurants |
| Blount County Schools | Blount | 1,800 | Public education system |
| U.S. Postal Service | Knox | 1,734 | Mail service |
| McGhee Tyson ANG Base | Blount | 1,717 | Air National Guard unit |
| UCOR | Roane | 1,600 | Engineering, environmental management & clean-up |
| Vanderbilt Mortgage & Finance | Blount | 1,600 | Manufactured homes financing |
| Cracker Barrel Old Country Store, Inc. | Regional | 1,598 | Restaurants and general stores |
| Copper Cellar Corp. | Knox | 1,576 | Full-service restaurants |
| CVS Caremark Corp. | Knox | 1,560 | Drugstores and pharmaceutical distribution |
| Jewelry Television | Knox | 1,500 | Satellite-based gem/jewelry home-shopping cable network |
| Newell Rubbermaid | Blount | 1,500 | Manufactures plastic office accessories |
| DTR | Claiborne | 1,495 | Rubber automobile hose |
| United Parcel Service (UPS) | Knox | 1,450 | Shipping and delivery operation |
| Summit Medical Group, PLLC | Regional | 1,424 | Primary care physician group |
| England Furniture | Claiborne | 1,400 | Furniture manufacturer |
| Lowe's Home Improvement | Regional | 1,250 | Home improvement warehouses and building supplies |
| Elavon | Knox | 1,239 | Electronic payment, processing service center |
| The Home Depot, Inc. | Regional | 1,228 | Home improvement warehouses and building supplies |
| SL Tennessee | Anderson | 1,150 | Manufacture gear shift assemblies, park brake levers, head & rear lights |
| Pellissippi State Technical Community College | Knox | 1,143 | Two-year technical community college. |
| Old Dominion Freight Line | Regional | 1,140 | Transportation - trucking |
| Scripps Networks (HGTV) | Knox | 1,057 | Cable networks - HGTV, Food Network, Do-It-Yourself, Fine Living & GAC |
| Wyndham Hotel Group | Regional | 1,056 | Hotel group |
| Hilton Worldwide | Regional | 1,052 | Hotel group |
| Anderson County Schools | Anderson | 1,050 | public education system |
| JTEKT Automotive TN-Vonore Co. | Monroe | 1,050 | Automotive steering systems |
| Roane County Schools | Roane | 1,050 | Public education system |
| Sitel | Anderson/Knox | 1,050 | Global customer interaction solutions provider |
| Target Corp. | Regional | 1,045 | Discount stores |
| Walgreens | Regional | 1,018 | Pharmacies and convenience stores |
| Knoxville Utilities Board (KUB) | Knox | 1,014 | Local utilities provider |
| Sears Holdings Corp. (Sears & Kmart) | Regional | 1,010 | Department stores |
| Arconic | Blount | 1,000 | Aluminum beverage can sheets |
| Oak Ridge Associated Universities | Anderson | 1,000 | University consortium, partnerships between scientific research, government & industry |
| Choice Hotels | Regional | 991 | Hotel groups |
| Burleson Brands | Regional | 975 | Full-service restaurants: Aubrey's, Sunspot, Bistro by the Tracks, Barley's Taproom, Stefano's Pizza |
| University Physicians Association Inc. | Knox | 952 | Physicians group |
| Weigel's Farm Stores Inc. | Knox | 950 | Service stations and convenience stores |
| Jefferson County Schools | Jefferson | 942 | Public school system |
| Collier Restaurant Group | Sevier | 900 | Restaurant operations |
| Chick-fil-A, Inc. | Regional | 887 | Fast food restaurants |
| Southeast Foods Co., LLC/Pennant Foods | Regional | 883 | Fast food restaurants |
| First Tennessee Bank | Regional | 882 | Banks |
| AT&T, Inc. | Regional | 864 | Telecommunications provider - telephone and internet. |
| Darden Restaurants | Regional | 855 | Full-Service Restaurants: Red Lobster, Olive Garden, Longhorn Steakhouse |
| Oak Ridge City Schools | Anderson | 850 | Local public education system |
| Marriott International | Regional | 809 | Hotel groups |
| Aisin Automotive Casting Tennessee Inc. | Anderson | 800 | Manufacture, casting, machining & assembly of timing chain covers, pistons, pumps, VVT's |
| Eagle Bend Manufacturing | Anderson | 800 | Manufactures auto body parts |
| Quality Home Health | Knox | 800 | Health Services - home health providers |
| InterContinental Hotels | Regional | 785 | Hotel group |
| DineEquity | Regional | 764 | Full service restaurants: Applebee's, IHOP |
| Brunswick Boat Group & Sea Ray Boats, Inc. | Knox/Monroe | 763 | Fiberglass pleasure boats |
| Texas Roadhouse | Regional | 755 | Full Service Restaurants |
| DeRoyal Industries | Knox | 747 | Manufactures medical devices and healthcare products |
| Charles Blalock & Sons, Inc. | Sevier | 740 | Hot and cold mix asphalt; ready-mix concrete |
| Helen Ross McNabb Center | Knox | 739 | Provider of mental health care, addiction recovery & social services |
| Subway | Regional | 739 | Fast food restaurants |
| Blount County Government | Blount | 733 | County government |
| Keurig Green Mountain | Knox | 726 | Manufacturer/distributor of single-cup beverages & brewers |
| ADT Security Services | Knox | 721 | Security system monitoring |
| Ingles Markets, Inc. | Regional | 715 | Grocery stores |
| Burger King Corp | Regional | 714 | Fast food restaurants |
| Dollar General Corp. | Regional | 714 | Retail trade - discount stores |
| OrthoTennessee | Knox | 707 | Health care |
| Radio Systems Corp | Knox | 705 | Manufactures pet containment & training products |
| Rural/Metro Corp. of Tennessee | Regional | 651 | Emergency ambulance and firefighting service |
| 21st Mortgage Corp. | Knox | 650 | Financing and servicing of manufactured home loans |
| Bush Brothers & Co | Knox, Jefferson | 650 | Manufacturing-Bush Beans and pet food |
| Exedy America Corp. | Knox | 650 | Automotive parts - torque converters |
| Sevier County Government | Sevier | 650 | County government |
| Monroe County Schools | Monroe | 648 | Public school system |
| Belk, Inc. | Regional | 644 | Department stores |
| Maryville City Schools | Blount | 641 | Government - Public School System |
| Wilderness in the Smokies | Sevier | 638 | Hotel & water park complex |
| Comcast of the South | Knox | 635 | Broadband telecommunications services |
| Cellular Sales | Knox | 631 | Service - largest Verizon wireless dealer |
| Kimberly-Clark Corp. | Knox/Loudon | 630 | Paper towels and bath tissue |
| Cherokee Health Systems | Knox | 627 | Health care service |
| G.C. Services | Knox | 620 | Service-financial services customer service center, collection agency |
| Bloomin' Brands, Inc. | Regional | 615 | Full service restaurants: Bonefish Grill, Carrabba's, Fleming's, Outback |
| YMCA of East Tennessee | Regional | 605 | Service - non-profit community organization |
| Diverse Concepts, Ltd. | Regional | 579 | Full service restaurants: Blue Moose, Bullfsih, Carino's, Harrison's, Lakeside, Mellow Mushroom, Parkside, Timberwood |
| Loudon County Schools | Loudon | 574 | public education system |
| Shoney's Restaurants | Knox | 573 | Full-service restaurants |
| Monterey Mushrooms, Inc. | Loudon | 570 | Mushrooms |
| O'Charley's Inc. | Regional | 565 | Full service restaurant |
| Regal Entertainment Group | Knox | 561 | Movie theaters |
| Hillcrest Healthcare Communities, Inc. | Knox | 559 | Long-term care, assisted living, short-term & long-term rehab services |
| Accenture Hospitality Services | Blount | 541 | Financial shared services center for Marriott International, Inc. |
| Carlex Glass Co. | Monroe | 536 | Manufactures automotive glass |
| U.S. Cellular Corp. | Knox | 533 | Cell phone, data systems and customer service center |
| National Fitness Center/Court South | Knox | 526 | Health club |
| Arby's | Regional | 525 | Arby's restaurants |
| Siemens Healthcare | Knox | 512 | Clinical imaging, preclinical & biomarker solutions |
| Fee Hedrick Family Entertainment | Sevier | 511 | Entertainment attractions |
| Mastercraft Boat Co | Monroe | 510 | Manufacturing - fiberglass leisure boats |
| Anderson County Government | Anderson | 507 | County government |
| Carlstar Group | Anderson | 500 | Manufacturing-industrial pneumatic tires for lawn, garden, heavy commercial vehicles |
| Science applications International Corp. (SAIC) | Anderson | 500 | Science & engineering consulting, energy, national security |
| ORNL Federal Credit Union | Regional | 497 | Credit union |
| Krystal Co. | Regional | 496 | Fast food restaurants |
| Ruby Tuesday, Inc. | Blount | 485 | Full-service restaurants |
| ConAgra | Cocke | 475 | Beans, tomato products |
| Energy Solutions | Anderson | 473 | Nuclear engineering services |
| Union County Schools | Union | 473 | Public school system |
| City of Oak Ridge | Anderson | 465 | Municipal government |
| Cheddar's Casual Café | Regional | 460 | Full service restaurant |
| Goodwill Industries | Regional | 460 | Service-donation centers; thrift stores |
| Papa John's Pizza | Regional | 460 | Fast food restaurants |
| Yamaha Jet Boat Manufacturing | Monroe | 452 | Manufactures sport boats |
| Connor Concepts | Regional | 450 | Full Service Restaurants: The Chop House, Connor's Steaks & Seafood |
| Crete Carrier Corp | Loudon | 450 | Transportation - trucking |
| FedEx (Express, Freight & Ground) | Knox | 450 | Package distribution - motor freight |
| Norfolk Southern Corp. | Knox | 450 | Railroad freight serving 22 states |
| Domino's Pizza | Regional | 447 | Fast food restaurants |
| Starbucks | Regional | 440 | Coffee shops |
| Home Federal Bank | Regional | 439 | Banks |
| Carlisle Tire & Wheel | Anderson | 432 | Lawn and garden, ATV, and commercial tires |
| Bojangles Restaurants | Regional | 430 | Fast food restaurants |
| Johnson University | Knox | 430 | 4 year private college |
| Roane State College | Regional | 430 | 2 year community college |
| JC Penney Co. | Regional | 427 | Retail Trade - department stores |
| Publix Super Markets | Regional | 420 | Grocery stores |
| Regions Financial Corp | Regional | 416 | Banks |
| Shoffner Kalthoff | Knox | 416 | Construction - mechanical & electrical contractor |
| Grainger Co Schools | Grainger | 409 | Public education system |
| Broadway Electric Service | Knox | 400 | Construction - electrical contractor |
| City of Pigeon Forge | Sevier | 400 | Municipal government |
| Knoxville News Sentinel | Knox | 400 | Newspaper publishing |
| Stokely Hospitality Enterprises | Sevier | 400 | Full service restaurants, resorts: Applewood Farmhouse Grill; Leconte Lodge; Edgewater Hotel; Baskin Robbins |
| Havco Wood Products | Monroe | 395 | Manufactures laminated wood floors for trucks |
| Knoxville Coca-Cola Bottling Co. | Knox | 382 | Bottling and soft drink distribution |
| BB&T Bank | Regional | 380 | Banks |
| Waffle House | Regional | 376 | Fast food restaurants |
| Leidos Engineering | Anderson | 375 | Engineering, energy management & clean/renewable energy consulting |
| Malibu Boats | Loudon | 372 | Manufactures wakeboard boats |
| Jim Pattison Group | Sevier | 371 | Ripley's area attractions |
| Pepsi Beverages Co | Knox | 368 | Manufacturing & transportation-soft drink bottling & distribution |
| Roane County Government | Roane | 366 | Municipal government |
| Knoxville TVA Employees Credit Union | Knox | 360 | Credit union |
| City of Gatlinburg | Sevier | 356 | Municipal government |
| Gold's Gym | Knox | 356 | Health club & fitness centers |
| Travelers Insurance | Knox | 356 | Personal lines insurance sales & service |
| Commercial Vehicle Group | Monroe | 350 | Manufactures seats for heavy trucks & motorcoaches |
| Custom Foods of America | Knox | 350 | Frozen foods |
| Great Smoky Mtns National Park | Regional | 350 | Government - National Park |
| House-Hasson Hardware | Knox | 350 | Transportation - hardware distribution |
| Kimble Chase Life Science | Roane | 350 | Manufactures laboratory glassware |
| Melaluca, Inc. | Knox | 350 | Manufactures detergents, dental care, nutritional supplements, personal care |
| Total Transportation of Mississippi | Loudon | 350 | Transportation - trucking |
| US Foods, Inc | Blount | 350 | Transportation-wholesale grocery distribution |
| Brinker International | Regional | 340 | Full service restaurants: Chili's Grill & Bar |
| HT Hackney Co. | Knox, Roane | 340 | Transportation - wholesale grocery distribution |
| WestRock (Rock-Tenn) | Knox | 337 | Manufactures folding paper boxes & displays |
| Bass Pro Shops | Sevier | 336 | Sporting goods store |
| City of Sevierville | Sevier | 332 | Municipal government |
| Kohl's Department Stores | Regional | 325 | Department stores |
| Jacobs Engineering Group | Anderson | 324 | Engineering Services |
| Loudon County Government | Loudon | 324 | Municipal government |
| Carson-Newman University | Regional | 320 | four year private college |
| Presbyterian Homes of TN | Knox | 320 | Retirement communities and nursing homes |
| SunTrust Bank | Regional | 320 | Banks |
| City of Maryville | Blount | 308 | Municipal government |
| Whirlpool Corp | Knox | 305 | Appliance repair customer repair center; service center |
| Dillard's Inc | Regional | 300 | Department stores |
| GE Power (Alstom Power) | Knox | 300 | Engineering-air quality control systems for power industry |
| K12 Inc | Blount | 300 | Virtual homeschooling academy support contact center |
| Rockford Manufacturing | Blount | 300 | Manufactures cotton, synthetic yarn, cordage |
| Averitt Express | Knox | 296 | Transportation - rrucking |
| Lenoir City Schools | Loudon | 292 | Public school system |
| Answer Financial Inc | Knox | 290 | Insurance customer service center |
| Michael Dunn Center | Roane | 290 | Service-Subcontracting, shredding, recycling, janitorial laundry service, temp service |
| Red Lobster Hospitality | Regional | 290 | Full service restaurants |
| Johnson Family of Restaurants | Sevier | 282 | Full service restaurants: Alamo Steakhouse, Bennett's BBQ, Big Daddy's, Mad Dogs', Mama's Farmhouse |
| TGIFriday's | Regional | 275 | Full service restaurants |
| Best Buy Co. | Regional | 273 | Electronics & appliances stores |
| Asbury Place at Maryville | Blount | 272 | Nursing home |
| DuPont Tate & Lyle | Loudon | 268 | Manufactures bio-products, corn syrup, ethanol |
| Camellia Home Health of East TN | Knox | 267 | Home healthcare |
| Big Lots Stores | Regional | 265 | Discount Stores |
| The TJX Companies | Regional | 258 | Department stores |
| Maryville College | Blount | 255 | 4 year private college |
| American Book Co. | Knox, Jefferson | 250 | Wholesale trade - books |
| Buddy's Bar-B-Q | Regional | 250 | Fast food restaurants |
| Federal-Mogul Sevierville | Sevier | 250 | Manufactures automotive engine valves |
| Republic Plastics | Knox | 250 | Manufactures plastic tableware & foam plates |
| Nelson Global Products | Anderson | 209 | Manufactures truck exhaust tubing & pipes |
| ARC Automotive | Knox | 190 | Manufactures automotive air bag actuators |
Source: Book of Lists, community websites 2018